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pre-clinical and clinical investigations of Sm14 are in Supplementary Table S2

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Acknowledgments Funding: This work was supported by the National Key Research and Development Program of China (2023YFC2508200), the National Natural Science Foundation of China (82373509, 82003384, and 82203960), Fundamental Research Funds for the Central Universities (2022CDJYGRH-003 and 2023CDJKYJH066), the Natural Science Foundation of Chongqing (CSTB2023JXJL-YFX0028), Chongqing Talents: Exceptional Young Talents Project (cstc2021ycjh-bgzxm0197), Inheritance and Innovation Team of TCM Treatment of Immune Diseases, Scientific Research Foundation from Chongqing University (02210011044110), and Research Horizontal Projects of Chongqing University (H20231432 and H20230936), China

When functioning properly, GLP-1 makes it easier to eat less and feel full on smaller portions