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& Eliasson, L

This trial, while not showing superiority of JTA-004 over placebo in the overall population, provides highly valuable insights into clinical trial design, placebo responses, and the potential need for better patient stratification in osteoarthritis research

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Smaller, more frequent meals (4-5 per day rather than 2-3) tend to be better tolerated with retatrutide than with tirzepatide, where 3 moderate meals often work fine