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Our patients at Centra Internal Medicine noticed modest weight reduction within the first four weeks of treatment

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Gastrointestinal adverse effects are common with GLP-1 RA therapy and are related to abrupt increases in drug plasma levels, which is clinically mitigated by gradual up-titration

95% CI, 0.93-4.02) after the index date compared with the non-GLP-1 RA medication group

Of note, Atg5/Atg7-dependent macroautophagy occurs predominantly at the level of early erythroblasts with mitophagy taking place during further erythroblast differentiation [56]