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Elias, A., Padinjakara, N

A significant advantage of GEMMs is that primary tumors which occur in such models are exposed to a functional immune system and a physiological tumor microenvironment, with subsequent BM occurring spontaneously [139]

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Without it, RBC precursors grow abnormally large (megaloblasts) and fail to mature

Biologically they are the same in terms of result just that they differ in terms of method of absorption