This is an ideal time to review your progress with your healthcare provider and discuss any side effects or response patterns that might inform next steps
Sesames website says that without insurance, Wegovy and Ozempic can cost as much as $1,600 a month
Despite these benefits, intensive glycemic control in patients with diabetes can worsen diabetic retinopathy, a phenomenon known as early worsening, which typically occurs within the first year of intensive treatment [11]
Microdosing means using well-below-standard starting doses of a GLP1 agonist to gain metabolic and neurologic benefits while minimizing side effects
Get baseline and follow up blood work
AHI reduction: Tirzepatide 15mg reduced apnea-hypopnea events by approximately 25-30 per hour vs 5 per hour for placebo Responder rate: Around 42% of tirzepatide participants achieved complete or near-complete resolution of sleep apnea events Weight loss: Average 18% body weight reduction accompanied the AHI improvements, consistent with SURMOUNT-1 data at comparable doses Source: Malhotra et al., NEJM 2024 Sleep Apnea Dosing vs Weight Loss Dosing The titration schedule is the same for both indications
