10.1038/s41419-019-1356-0 156 NapolitanoG.EspositoA.ChoiH.MatareseM.BenedettiV.di MaltaC.et al (2018)
Among those markets, India and China alone represent about a quarter of the worlds adult obese population, and the availability of generic semaglutide will be a big shift in how these countries manage these populations, Arias says
Shrinks fat cells in mice In diet-induced obese mice, 11 days of 5-Amino-1MQ (subcutaneous, around 34 mg/kg/day) reduced body weight, total fat mass, and plasma cholesterol with no drop in food intake or lean mass
Reduces Inflammation and Oxidative Stress This directly slows CKD progression
Sphingosine kinase1 involves the inhibitory action of HIF1 by chlorogenic acid in hypoxic DU145 cells
GLP-1 therapies have already shown efficacy in reducing major adverse cardiovascular events and slowing kidney disease progression in people with diabetes and obesity