The mechanism involves gene regulation in chondrocytes (cartilage cells) - Cartalax binds to specific DNA sequences in cartilage tissue, upregulating genes for cartilage matrix proteins (collagen type II, proteoglycans, aggrecan), downregulating inflammatory and degradative enzymes (matrix metalloproteinases), and optimizing the balance between cartilage formation and breakdown
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Back Barany, G, Barany, MJ (27 Sept 2024) 'Foundational contributions of Svetlana Mojsov to the GLP-1 field', Explorations of Drug Science , 2, 688700
To determine whether the spindle-shaped fibroblasts seen in Figure 4 were activated PSCs, we performed double-staining of -SMA and GLP-1R in an area showing fibrosis (Figures 5ad)
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If one relies solely upon the EPIC report, any detectable cardiac enlargement is sufficient to start the drug