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Additionally, women with active moderate to severe vaginitis or other significant infections, gynecologic conditions affecting study procedures, unresolved sexual trauma or abuse histories, or prior hysterectomies involving menstrual cycle alterations were not eligible

FDA in 2002, for the symptomatic treatment of BPH after significant serum DHT suppression (94.7%3.3% ) in Phase II, double-blind, placebo controlled, comparative dose-ranging trial, greater than with finasteride (70.818.3%, p 90% by forming a stable complex with a slow rate of dissociation constant [39]

However, because many conditions can cause late or missed periods, its important to have a thorough evaluation

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