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C., Baker D., Hodges J

& Hurko, O

A companion phase III trial reported a -10.9% reduction in visceral adipose tissue (a 21 cm decrease) in the tesamorelin group compared with -0.6% in the placebo group over the six-month efficacy phase, alongside significant improvements in trunk fat, waist circumference, and waist-hip ratio, with the authors concluding that tesamorelin reduces visceral fat by approximately 18% and improves body-image distress in HIV-infected patients with central fat accumulation, without significant side effects or disruption of glucose control

As of April 2025, the NHC had further issued the Notice on the Establishment and Management of Weight Management Clinics, ()

doi: 10.1038/onc.2015.32 79 ChiangSKChenSEChangLC