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Targeting sequences were as follows: Idh1 : GUACAACCAGGAUAAGUCAAUUGAA, GUUGAAGAAUUCAAGUUGAAACAAA

Ma X, Tian Y, Yang R, Wang H, Allahou LW, Chang J, Williams G, Knowles JC, Poma A

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Acknowledgements Work discussed in this Review was supported by a Wellcome Trust Senior Investigator Award (095531), the Knut and Alice Wallenberg Foundation, the Swedish Research Council, the Hartwell Foundation for Biomedical Research (201500731), the Juvenile Diabetes Research Foundation (CDA-2-2013-54) and the US NIH (DK110276)

Independent testing across multiple vendors and compounds has revealed that weight accuracy issues are widespread

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