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While animal studies cannot definitively rule out human cancer concerns, the consistent absence of tumors or pre-cancerous changes across multiple species, dosing regimens, and administration routes carries meaningful weight

By influencing not just inflammation and oxidation but also immune function, neuronal signaling, epithelial regeneration, and microbial ecosystems, plant-derived compounds serve as holistic and promising therapeutic agents in the treatment of GI disorders

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Oxygen sensing, homeostasis, and disease