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The researchers suggest that reduced inflammation and improved metabolism may help explain the link

10.1016/j.molmet.2017.02.002 81

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Participants with the highest body mass index (BMI) values (40 or above) were most likely to access semaglutide, which is not surprising given that this group has the highest risk for developing further metabolic diseasebut Podolsky says it reflects a trend that physicians may be restricting GLP-1 drugs to patients with the highest weight, and solely recommending lifestyle interventions to patients with BMI values of 35 or less