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It is a requirement in the United States for females with childbearing potential to remain on at least two forms of contraceptives while on [isotretinoin] treatment, Blalock and colleagues wrote in the Journal of Drugs in Dermatology

Zhu A, Andino J, Daignault-Newton S, Chopra Z, Sarma A, Dupree JM

Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B, OKeefe SJ

In addition, recent clinical evidence from the AngioSafe T2DM Study demonstrated no association between GLP-1 RAs and severe diabetic retinopathy [107], suggesting that GLP-1 RA does not have a causal influence on retinopathy independent of glucose lowering

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However, always do a patch test before the entire application