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As illustrated in Additional file 1: Figure S1C, animals from both TAT and TAT-DAT NT did not differ in time spent in each duration (two-way ANOVA with repeated measures, F 1, 10 = 0.321, p = NS), suggesting that the differences in spontaneous alternation behavior were unlikely due to confounding factors such as anxiety

These processes can affect the peptides structural integrity and potentially affect analytical results (Sigma-Aldrich, 2023b)

It says most manufacturers classify these agents as contraindicated during pregnancy and lactation until further data emerges, and it characterizes that as conservative regulatory guidance rather than confirmed harm

A separate trial linked the same GHRH approach to gains in lean body mass, though its approved use stays narrow

It depends on your risk and the procedure