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During any weight loss whether medication-assisted or not the body loses both fat and lean tissue

It acts centrally on hypothalamic neurons to suppress appetite, increase energy expenditure, and shift metabolism toward catabolic pathways while inhibiting anabolic responses

Clinical studies have shown significant reductions in body weightup to 15% or more over timemaking it one of the most effective non-surgical treatments available

For In Vitro Research Use Only Not for Human or Veterinary Use Intended Use: This compound is intended strictly for in vitro laboratory research

Contrave (naltrexone/bupropion) : This convenient once-daily tablet aids in weight loss by promoting satiety

1997: Pollard et al