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Transglutaminase 2 (Tgm2) covalently cross-links IB, further promoting NF-B nuclear translocation and enhancing the expression of phosphorylated p53 and p21

According to Eli Lilly, the randomised, double-blind trial included groups of participants on three different doses 6 mg, 12 mg, and 36 mg as well as a placebo group

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