GLP-1 agonists work by mimicking a naturally occurring hormone that regulates blood glucose levels, enhances insulin secretion when blood sugar is elevated, suppresses glucagon release, and slows gastric emptying
35 Without this stimulus, especially during a calorie deficit potentially exacerbated by GLP-1 effects, the body may be less efficient at utilizing dietary protein for muscle maintenance, leading to greater lean mass loss
Lilly's next-gen Triple G (GLP-1/GIP/glucagon) agonist (Phase 1b, Phase 2): started recruiting for a Phase 3 trial this year approvals are expected by 2026
G., Contreras, V., Menini, T., & Gugliucci, A
Exercise and glucagon-like peptide-1: Does exercise potentiate the effect of treatment
For a full overview of how strength training fits into your GLP-1 plan, visit our complete guide to strength training on Ozempic and Wegovy