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The SUSTAIN-5 trial followed patients for over 4 years with sustained efficacy and a stable side effect profile

From a bulk purchasing perspective, tirzepatide is currently more readily available than retatrutide through both pharmaceutical and research channels, since tirzepatide already has FDA approval (as Mounjaro for type 2 diabetes and Zepbound for weight management)

When combined with comprehensive psychological and lifestyle support, patients lose meaningful amounts of weight at lower doses

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