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Following each experiment, the cells were washed once with PBS (LPS solution CBP007B) and fixed with 10% formalin solution (Sigma HT501128-4L) for 10 min at room temperature

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This series of signal transductions ultimately regulates the expression of microphthalmia-associated transcription factor (MITF), thereby initiating the transcription and production of melanin synthesis-related enzymes, laying the foundation for melanin synthesis