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Clinical data shows that users consume less food, which contributes significantly to consistent weight loss

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Treatment with TIR (HG-TIR) prevented HG-induced changes observed in mRNA expression and protein of glucose transporters and insulin sensitivity marker levels

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In the gut, they decrease secretion of ghrelin (the hunger hormone) and increase peptide YY and cholecystokinin levels

[1] In 2024, global spend on anti-obesity medication exceeded $30 billion for the first time, which is over a ten-fold increase since 2020, as reported by IQVIA