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After establishing an obesity model, mice were further divided into six groups: control group, liraglutide (LIRA) group, semaglutide (SEMA) group, high-fat diet (HFD) group, HFD + LIRA group, HFD + SEMA group, and subcutaneous injection for 4 weeks

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In the process of inhibiting ferroptosis, FSP1 and dihydroorotate dehydrogenase (DHODH) act on the plasma membrane and mitochondrial inner membrane, respectively, to reduce ubiquinone (CoQ) to ubiquinol (CoQH2) (Koppula et al., 2022)