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The addition of the acetyl group also endows acetyl L-carnitine (ALC) with a greater solubility in water, which enables it not only to diffuse easily across the inner wall of the mitochondria and into the cell cytosol, but also cross cell membranes in general more easily

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Acknowledgements Tahereh Jasemizad would like to thank The University of Auckland for providing her PhD scholarship to undertake the project

Metabolic Factors, lifestyle habits, and possible polyneuropathy in early type 2 diabetes: a nationwide study of 5,249 patients in the danish centre for strategic research in type 2 diabetes (DD2) cohort

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doi: 10.1016/j.fitote.2014.08.001, 43