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Metabolic rebound after GLP-1 receptor agonist discontinuation

[DOI] [PMC free article] [PubMed] 3.I.A

Semaglutide has been studied extensively, Gerstein said

Further mechanistic studies have shown that the regulatory effect of -HB depends on a novel epigenetic modification, Kbhb

By the end of this window, average weight loss in clinical trials commonly reaches around 58% of baseline body weight, though the range is wide