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Definitions, classification, and epidemiology of obesity
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Baxter, S
Hazard ratios comparing the tirzepatide with the semaglutide groups were 1.76, 2.54 and 3.24 for 5%, 10% and 15% or more weight loss, respectively [5]
However, concerns are emerging related to the potential loss of muscle mass linked to these treatments, with significant implications for long-term health, as came out of a recent editorial in the prestigious journal The Lancet entitled Muscle matters: the effects of medically induced weight loss on skeletal muscle, which underlined how GLP-1 receptor agonists have revolutionized the treatment of obesity and proven to be effective in reducing body weight
