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Chronic or excessive alcohol intake can reduce the bodys ability to replenish glutathione naturally

& Ashonibare, P

M., An, J

Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection

Lactobionic acid also exhibits significant antioxidant activity

Glutathione is present in millimolar concentrations in most mammalian cells and it is involved in several fundamental biological functions, including free radical scavenging, detoxification of xenobiotics and carcinogens, redox reactions, biosynthesis of DNA, proteins and leukotrienes, as well as neurotransmission/neuromodulation