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Heart Health and Blood Pressure A systematic review pooling 11 clinical trials involving nearly 600 adults found psyllium modestly but consistently lowered systolic blood pressure by about 2 mmHg, particularly in individuals already diagnosed with hypertension

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18 However, its rapid hydrolysis by intestinal lactase and SGLT1 inhibition causing diarrhea limited its clinical use

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GLP-1 peptide agonists are efficacious drugs for the treatment of diabetes