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Metabolic Dysfunction and Oxidative Stress in Epilepsy

Besides lowering A1C, GLP-1s have demonstrated additional benefits, including modest weight loss and reduced risk of major adverse cardiovascular events (MACE)

Moreover, the incremental increase in dosage is directly correlated with the extent of weight loss

Nicotinamide adenine dinucleotide and the sirtuins caution: Pro-cancer functions

Preclinical and clinical studies have indicated that GLP-1 receptor agonists can ameliorate kidney function by reducing inflammation, oxidative stress, and fibrosis, which are key contributors to diabetic nephropathy