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The indirect interaction of ZO proteins with the cytoskeleton involves several actin-binding proteins including cortactin (Katsube et al., 1998), alpha-catenin (Muller et al., 2005), protein 4.1R (Mattagajasingh et al., 2000), the Ras target, AF6/afadin, as well as the actin- and myosin-binding proteins, cingulin (D'Atri et al., 2002) and Shroom (Etournay et al., 2007)

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Kazemi, A., Shojaei-Zarghani, S., Eskandarzadeh, P., & Hashempur, M

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Mitochondrial quality control mechanisms have been recently found to control cellular identity and maturity in metabolically relevant tissues 60 , including in pancreatic -cells, highlighting the importance that mitochondria have in the control of -cell function