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Instead, GIP may counteract nausea and vomiting via direct modulation of the area postrema/NST emesis circuitry (169) and exert protective effects on unfavorable altered gut motility (44)

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Activation of GLP-1R suppresses food intake and induces postsynaptic depolarization of membrane potential (Figure 1A) and/or presynaptic modulation of glutamatergic or GABAergic neurotransmission (Figure 1B)

The Role of Erythritol and Xylitol in Stimulating GLP-1 Gastrointestinal Hormones: Implications for Appetite Regulation by Thom King, Icon Foods, Chief Innovations Officer/Food Scientist Erythritol and xylitol are sugar alcohols (polyols) widely used as low-calorie sweeteners