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Independent of L-carnitine supplementation, basal respiration ( Figure 8A ) was significantly higher 14 d after in vivo LPS administration than before and 24 h after the injection

This was the first demonstration that a GLP-1R agonist produces cardiovascular benefit independent of glycaemic effects, expanding the research interest in GLP-1R agonism beyond metabolic and weight endpoints

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Many people struggling with weight carry a biological drive to eat more, and GLP-1s can calm that signal