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Tesofensine APPETITE SUPPRESSANT / WEIGHT LOSS SUPPORT / MOOD-STABILIZER Mechanism of Action: Tesofensine is a triple monoamine reuptake inhibitor (T-MRI) that increases levels of dopamine, norepinephrine, and serotonin in the brain

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These combinations are entirely off-label and have not been studied at scale in controlled trials

Angiotensin II- and IV-induced changes in cerebral blood flow

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limited data exists beyond 12 weeks