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doi: 10.1097/RHU.0000000000000502 150 SolomonDHGargRLuBToddDJMercerENortonTet al
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23,24 The spatial precision conferred by -Klotho thus ensures that endocrine FGF21 signalling remains physiologically specific despite widespread FGFR distribution
both lead to abnormal cerebral blood flow and disrupt the delivery of oxygen and glucose, resulting in cellular dysfunction, such as mitochondrial oxidative phosphorylation and bioenergetic stress (Zheng J
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