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Since co-treatment of UK-5099 and JMF4073 depleted dTTP pool and suppressed the growth of T315-Bcr-Abl-32D cells, we proposed that reducing GSH biosynthesis induces not only oxidative stress but also replication stress in tumor cells, which demands the synthesis of dTTP and dCTP for survival

Lack of Sleep Lack of sleep is associated with some extremely negative health consequences, including heart disease, diabetes, obesity, depression, and even certain types of cancer

comparison of exon/intron organization with other mammalian and fungal CYP genes

Miami New Times

Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway

Hippocampal pdha1 gene knockout inhibits the warburg effect leading to cognitive dysfunction and attenuates the beneficial effects of zibupiyin recipe on cognition