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Sometimes lifestyle changes are enough to improve appetite, energy, and weight patterns

doi: 10.1038/nature06880 120 DaskovaNModosIKrbcovaMKuzmaMPelantovaHHradeckyJet al

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Side effects were dose-dependent, which is why the dose is titrated upward gradually rather than starting at the full dose

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Rehfeld JF, Knop FK, Asmar A, Madsbad S, Holst JJ, Asmar M