The disease pattern alternates between relapses (acute autoimmune attacks) and remissions (partial recovery periods), at least in the relapsing-remitting form that accounts for about 85% of initial MS diagnoses
10.1016/j.celrep.2016.12.090 Cell Rep
Thus, this competition may reflect a naturally evolved mechanism to efficiently co-regulate inflammatory versus anti-inflammatory pathways, fine-tuning the extent of an inflammatory response
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Chang JY, Komaki R, Wen HY, Xiang Z, Allen PK, DeGarcia B, Bluett JB, Lu C, Tsao A, Swisher SG , Gillin M, Mohan R, Cox JD