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Little is known about the biochemical functions of this CYP subfamily

What it transports: Methylfolate (nature's preferred form) Folinic acid (therapeutic form) Folic acid (BLOCKS this pathway) Transport #2: Proton-Coupled Folate Transporter (PCFT) Supporting Route (10-20%) PCFT handles 10-20% of transport and becomes critical when FR is impaired

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Another strategy involves modifying the peptide itself

If you have vitamin B12 deficiency, your doctor may recommend vitamin B12 injections as a treatment option