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As expected 31,32 , GLP-1-G 2 ( 1 ) was 2.5 times less potent than GLP-1, with still a 50% effective concentration (EC 50 ) of 0.24 nM

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Each reviewer was required to describe in detail the reasons that downgrading the classification of evidence based on the principle of evaluation

GLP-1 is a naturally occurring hormone that helps regulate blood sugar levels by stimulating insulin secretion and inhibiting glucagon release, thus lowering blood glucose levels