The most common side effects include nausea (50-60% of users, most common during dose escalation but usually resolves within 2-4 weeks at each dose level), vomiting (25-30%, often transient and manageable), diarrhea (25-30%, usually mild and self-limiting), constipation (15-20%, manageable with dietary adjustments), and decreased appetite (20-30%, which is a desired effect but can be intense first)
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However, kidney function declines with age, which affects clearance of some peptides

The binders with the most supportive data showing effectiveness for mycotoxins are Cholestyramine (CSM or brand Questran) 1/16 tsp every other day, increasing up to 1 scoop 4x/day Colesevelam (CSV or brand Welchol) 625mg 1/4 tab daily, increasing up to 2 tabs 3x/day taken with food has 1/4 the binding capacity as CSM Other binders Activated charcoal portion of 500mg capsule daily, increasing up to 1 cap 3x/day Bentonite clay 1/16 tsp liquid, increasing up to 1 cap 3x/day Chlorella 200mg, 1/8 tablet every other day, increasing up to 1 cap 3x/day Optifiber lean 1/4 scoop daily, increasing up to 1 scoop 3x/day Saccharomyces boulardi 1/4 capsule with food daily, increasing up 1 capsule 3x/day with meals Mycotoxins bind best to certain binders Ochratoxins cholestyramine, colesevelam, charcoal Trichothecenes / Aflotoxins charcoal, bentonite clay, chlorella Gliotoxins bentonite clay, saccharomyces boulardii, N-acetyl-cysteine Zearalanone / Enniatin B: bentonite clay, saccharomyces boulardii Dietary and environmental considerations Key is to avoid giving molds the sugars they need to survive

I loss pounds, and my overall fat loss is excellent
Aug 2015;27(8):1127-37