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Why it matters clinically: The speculation surrounding Kardashian became a cultural entry point for public awareness of GLP-1 receptor agonists

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Yes IGF-1 LR3s anti-catabolic effects can help preserve lean muscle mass during caloric restriction by maintaining protein synthesis signaling even when energy availability is reduced

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Mir Ali, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in California, said GLP-1 medications have changed the medical landscape, especially in the treatment of obesity