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These findings highlight the importance of considering sex as a biological variable when using the 3xTg-AD model to study AD pathogenesis and develop potential therapeutic interventions

An alternative route is activated in situations where conversion of -glutamyl-L-cysteine into GSH is insufficient

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Carbomer was used in place of HPMC as polymer / gelling agent and placebo transdermal gels are prepared as provided in comparative example 2

They often start with a higher dose, then get smaller doses based on how they do

Single-compound intervention arms with saline controls are the most common design in the published literature