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In human clinical trials, individuals ingesting ME-3 for two weeks gained a remarkable 49% increase in the ratio between reduced to oxidized glutathione

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Neither has published cardiovascular-event or mortality outcomes

10.1021/bi011459o Biochemistry 104 PompellaA.CortiA.PaolicchiA.GiommarelliC.ZuninoF

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In fact, glutathione levels seem to help support a healthy immune response. For example, one study found that glutathione helps "fine-tune the innate immune response." Another study found that glutathione supplementation enhanced markers related to immune response. In part, this potential benefit is because of glutathione's antioxidant properties