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After 18 months of treatment, the patient's cognitive function test scores improved from 2/12 in the average category at baseline to 7/12 in the average category, demonstrating substantial cognitive enhancement

No randomised controlled trials

Common causes include: Pernicious anaemia Conditions affecting absorption in the stomach or intestines Certain medications Dietary insufficiency, particularly in strict vegan diets Increasing age Identifying the underlying cause is important because treatment recommendations may vary

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How Common is Vitamin B12 Deficiency and When is a Blood Test Needed

The combination of timing and dose strongly suppresses slow-wave sleep and substantially blunts the nighttime GH pulse