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Obesity: a much higher study focus than other metabolic disease areas Precisely classifying the clinical trial types in the metabolic domain can be a fraught affair given the variability of descriptions, but taking a conservative approach to classification clearly reveals that trials involving obesity and overweight outnumber those focused more on type 2 diabetes about four to one

Several studies have estimated the costeffectiveness of GLP1s for obesity from a healthcare perspective, considering costs for screening and treatment against savings from improved weight and health outcomes and corresponding longterm reductions in healthcare utilization, including downstream accumulated health benefits

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