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The demonstration that its availability can be readily manipulated in humans, and impacts on physiological function, will result in renewed business and scientific interest in this compound...However, research over the past decade has shed new light on the importance of carnitine as a regulator of skeletal muscle fuel selection and physiological function. Ferreira GC and McKenna MC, L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. in Neurochemical Research , Volume 42, Issue 6, June 2017, pp 1661 - 1675

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ATP is required to synthesize Glutamine (Gln) from Glutamate (Glu) and to recycle GABA in astrocytes ( Figure 6 )

10.1080/17435889.2025.2520736 98 JacobS.KatherF

Kinney JW, Bemiller SM, Murtishaw AS, Leisgang AM, Salazar AM, Lamb BT