(More information) Vitamin B 12 is essential for the preservation of the myelin sheath around neurons and for the synthesis of neurotransmitters
The increased risk of amputation seen in the large, long-term Canagliflozin Cardiovascular Assessment Study (CANVAS) trial for canagliflozin, and select observational studies, merits further research but overall, there is currently no consistent evidence of SGLT2i exposure and increased risk of amputation
Improvements were seen in individual MACE components (secondary endpoints): superior reductions were seen in nonfatal stroke for sc semaglutide in SUSTAIN 6 (HR 0.61 [95% CI: 0.380.99]) and for dulaglutide in REWIND (HR 0.76 [95% CI: 0.610.95]), and in CV death for liraglutide in LEADER (HR 0.78 [95% CI: 0.660.93]) and for oral semaglutide in PIONEER 6 (HR 0.49 [95% CI: 0.270.92])
The phone barely rings before going to a generic voicemail, and I never received a call back
What research does show is the opposite of reassuring for fans of tiny doses
Toward A Unified Dopamine-Morphine-GLP-1 Hypothesis The most parsimonious interpretation of these findings is that dopamine, endogenous morphine, and GLP-1 signaling participate in a partially overlapping evolutionary network that coordinates acquisition, valuation, and energetic stabilization
