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While recent high-quality reviews have extensively covered the general crosstalk between GLP-1 signaling and the gut microbiota, or focused broadly on pharmacomicrobiomics in metabolic diseases, a comprehensive critical evaluation centered on therapeutic heterogeneity remains scarce

As a clinically backed method for weight loss, semaglutide has enabled millions to shed significant weight and improve their overall health

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Once-weekly semaglutide in adults with overweight or obesity (STEP 1)