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10.3390/molecules22060929 150 LiuY.ZhouJ.HuY.WangJ.YuanC

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Comparison of steady state development and reduction of menopausal symptoms after oral or transdermal delivery of 17--estradiol in young healthy symptomatic menopausal women

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The authors proposed multiple potential mechanisms including interactions with opioid, GABAergic, and monoaminergic systems, establishing the conceptual framework for subsequent mechanistic research into DSIP's neurophysiological actions