45 Additional studies confirmed that N-AcGIP, another long-acting GIP agonist, 46 decreased osteoclast-mediated bone resorption and enhanced cortical bone quality in rodents
J Cell Physiol 230:30093018 [DOI] [PubMed] [Google Scholar] 62.Yu J, Shi YC, Ping F, Li W, Zhang HB, He SL, Zhao Y, Xu LL, Li YX (2021) Liraglutide inhibits osteoclastogenesis and improves bone loss by downregulating Trem2 in female type 1 diabetic mice: findings from transcriptomics
GLP-1R activation has a significant effect on glycemic control in patients with T2DM through a variety of mechanisms, including stimulation of insulin secretion, inhibition of glucagon secretion, protection of -cells from apoptosis, slowing gastric emptying and increasing satiety (Drucker, 2006)
Initial weight loss typically occurs within the first month, with ongoing, steady progress over the following months
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Both of these effects slow down the rate at which food is digested and make you feel fuller