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In a study of 55 French patients with mast cell disorders, 43 patients achieved a "best response" and 76.7% of the responding patients achieved a persistent response (three months or longer.) [34] Median time to first response was 2 months and median time to best response was 6 months

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Negatively charged amino acids: The side chain of amino acids has an extra carboxyl group with a dissociable proton