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A landmark 2023 New England Journal of Medicine trial found that semaglutide significantly reduced the risk of major adverse cardiovascular events among adults with overweight or obesity, even in the absence of diabetes (NEJM, 2023)

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the aforementioned trials, designed for evaluating the effect of l-ARG supplementation, used standardized OLeary and KEED questionnaires, addressing the overall sexual function by including erectile and ejaculatory function evaluated during both sexual activity with the partner and masturbatory activity

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If side effects are problematic, we adjust extending the time at a dose, adding supportive measures, or exploring a medication switch